ABBREVIATIONS

 

List of commonly used abbreviations, in alphabetical order:

 

A

ACTH = adrenocorticotropic hormone

ANS = autonomic nervous system

APP = acute phase protein

-APP = negative acute phase protein

+APP = positive acute phase protein

AR = apparent recovery

AZF = adrenal zona fasciculate

 

C

cAMP = 3',5'-cyclic monophosphate

CAR = cortisol awakening response

CBG = corticosteroid binding globulin

CCα = decision limit

CCβ = detection capability

CNS = central nervous system

CORT = cortisol

CR = corticosteroid receptor

CRH* = corticotropin releasing hormone (*= both CRF and CRH are used)

CRM = certified reference material

 

E

EDC = endocrine disruptor chemical

EIA = enzyme immunoassay

ELISA = enzyme-linked immunosorbent assay

ESI+ = electrospray ionization positive mode

ESI- = electrospray ionization negative mode

ESRF = European Synchrotron Radiation Facility

 

G

GC = glucocorticoid

GFP = green fluorescent protein

gGR = genomic glucocorticoid receptor

gMR = genomic mineralocorticoid receptor

GnRH = gonadotrophin-releasing hormone

GR = glucocorticoid receptor

GRE = glucocorticoid response element

 

H

HA = hydroxyapatite

hbc = hours before challenge

hGR = human glucocorticoid receptor

hMR = human mineralocorticoid receptor

hpc = hours post challenge

HPA = hypothalamic-pituitary-adrenal

HPI = hypothalamic-pituitary-interrenal

HPLC = high-performance liquid chromatography

3α-HSD = 3α-hydroxysteroid dehydrogenase

3β-HSD = 3β-hydroxysteroid dehydrogenase

11β-HSD = 11β-hydroxysteroid dehydrogenase

Hsp = heat shock protein

 

I

IA = immunoassay

IFN = interferon

IL = interleucin

IL-1 = interleucin-1

 

K

k = coverage factor

K factor = Fulton’s condition factor

 

L

L = standard length

LC = liquid chromatography

LC-MS/MS = liquid chromatography coupled to tandem mass spectrometry

LLE = liquid-liquid extraction

LOD = limit of detection

LOQ = limit of quantitation

 

M

MC = mineralocorticoid

MC2R = melanocortin 2 receptor

ME = matrix effects

mGR = membrane glucocorticoid receptor

MIP = molecularly imprinted polymer

mMR = membrane mineralocorticoid receptor

MNE = mean normalized expression

mPVN = magnocellular subdivision of PVN

MR = mineralocorticoid receptor

MRM = multiple-reaction monitoring

mRNA = messenger RNA

MS = mass spectrometry

MS-222 = methane tricaïne sulfonate

MS/MS = tandem mass spectrometry

m/z = mass to charge

 

N

Na+/K+-ATPase = sodium/potassium-activated adenosine triphosphatase

NADP+/NADPH = nicotinamide adenine dinucleotide phosphate

NCP = non-collagenous protein

NF-κB = nuclear factor-κB

nGRE = negative GRE

ns = not specified

 

P

P = proximal

PBS = phosphate buffered saline

POMC = proopiomelanocortin

PP = protein phosphatase

pPVN = parvicellular division of PVN

pre-mRNA = precursor mRNA

PTM = post-translational modification

PVN = paraventricular nucleus

 

Q

qPCR = real-time polymerase chain reaction

 

R

R2 = correlation coefficient

RAS = renin-angiotensin system

RIA = radio immunoassay

RNA = ribonucleic acid

RT = retention time

 

S

SCN = suprachiasmatic nucleus

S/N = signal to noise

SNS = sympathetic nervous system

SPE = solid phase extraction

StAR = steroidogenic acute regulatory protein

 

T

TBP = TATA-binding protein

THE = 5β-tetrahydrocortisone

THF = 5β-tetrahydrocortisol

THS = tetrahydro-11-deoxycortisol

TNFα = tumor necrosis factor α

 

U

U = expanded measurement uncertainty

uc = combined measurement uncertainty

UPLC-MS/MS = ultra-performance liquid chromatography coupled to tandem mass spectrometry

UV = ultraviolet

 

V

VC = variation coefficient

 

W

WBC = whole body cortisol

 

X

XAS = X-ray absorption spectroscopy

XRF = X-ray fluorescence