Glucocorticoid profiling of commercially available Artemia


StressChron Framework:

Project code061
Research areaUnravelling the impact of chronic stress across vertebrates
Research topicFeed as stressor focusing on invertebrates (e.g. Artemia), mycotoxins and
fish feed constituents
SpeciesArtemia franciscana (Great Salt Lake, USA), parthenogenetic strain (Bolshoye
Yarovoye, Russia), Artemia tibetiana (Lagkor Co, Tibet and China)



The research goal is to assess the glucocorticoid profile by ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS) in a wide range of Artemia samples present in the cyst bank of the Artemia Reference Center of Ghent University to biologically validate the finding that Artemia contain glucocorticoids. All samples are commercially available hereby representing different species and locations and include: (i) 69 samples of Great Salt Lake, USA (sexual Artemia franciscana); (ii) Bolshoye Yarovoye, Russia (parthenogenetic strain); and (iii) Lagkor Co, Tibet and China (sexual Artemia tibetiana). These findings are of potential interest for the aquaculture industry as these vertebrate stress hormones are most likely to be trophically transferred from Artemia to the fish larva, hereby possibly influencing early life development and the ontogeny of the hypothalamic-pituitary-interrenal (HPI) axis and molecular regulation of the glucocorticoid mediated stress response in fish larvae. As a consequence, unravelling the role of glucocorticoids in Artemia is pivotal from an (in)vertebrate physiological point of view and with respect to creating a more sustainable aquaculture.



Keywords: aquaculture, fish, larva, Artemia, stress, glucocorticoids

Funding: internal

Status: on-going


Ghent University, Belgium (Aerts J, Van Stappen G)

Flanders Research Institute for Agriculture, Fisheries and Food, Belgium (Aerts J)



None at present